oxacillin mic oxacillin conc (ATCC)
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Oxacillin Mic Oxacillin Conc, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 17828 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 17828 article reviews
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1) Product Images from "A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to ß-Lactam Antibiotics"
Article Title: A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to ß-Lactam Antibiotics
Journal: ACS infectious diseases
doi: 10.1021/acsinfecdis.0c00307
Figure Legend Snippet: Bioassay-guided fractionation of C. americana for synergy with oxacillin for growth inhibition of MRSA (LAC). Fractions with no FICI values (gray color) or no MIC values were screened for growth inhibition and synergy at single concentrations, but not investigated further. Yield for each fraction is calculated relative to parent; yield of crude extract 649 is relative to dry plant material.
Techniques Used: Bioassay, Fractionation, Inhibition
Figure Legend Snippet: A) Time-kill assay of 1 and oxacillin against MRSA (LAC). The treatments displayed in this figure are ¼ MIC of 1 and ¼ MIC oxacillin alone and in combination, and DMSO, the vehicle control. B) Time-kill assay repeated with oxacillin concentrations at the susceptibility breakpoint (2 μg/mL).
Techniques Used: Time-Kill Assay, Control
Related Articles
Concentration Assay:Article Title: A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to ß-Lactam Antibiotics Article Snippet: .. Against ATCC strains, compound 1 lowered the oxacillin MIC 16–512-fold at a concentration of 5 μg/mL; notably, 1 did not exhibit synergy with oxacillin against the oxacillin-susceptible S. aureus AR Bank #0470 and oxacillin-intermediate S. aureus AR Bank #0474. table ft1 table-wrap mode="anchored" t5 Table 1. caption a7 LAC and AR Bank Strains MIC Alone (μg/mL) MIC In Combination (μg/mL) FICI Compound 1 Oxacillin Compound 1 Oxacillin LAC 16 64 2 1 0.141 AR Bank #0470 16 4 8 0.625 0.65 AR Bank #0474 16 8 8 1 0.625 AR Bank #0480 16 32 4 1 0.283 ATCC Strains MIC Alone (μg/mL) Oxacillin MIC In Combination with 1 (μg/mL) Fold Reduction of Inhibition:Article Title: A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to ß-Lactam Antibiotics Article Snippet: .. Against ATCC strains, compound 1 lowered the oxacillin MIC 16–512-fold at a concentration of 5 μg/mL; notably, 1 did not exhibit synergy with oxacillin against the oxacillin-susceptible S. aureus AR Bank #0470 and oxacillin-intermediate S. aureus AR Bank #0474. table ft1 table-wrap mode="anchored" t5 Table 1. caption a7 LAC and AR Bank Strains MIC Alone (μg/mL) MIC In Combination (μg/mL) FICI Compound 1 Oxacillin Compound 1 Oxacillin LAC 16 64 2 1 0.141 AR Bank #0470 16 4 8 0.625 0.65 AR Bank #0474 16 8 8 1 0.625 AR Bank #0480 16 32 4 1 0.283 ATCC Strains MIC Alone (μg/mL) Oxacillin MIC In Combination with 1 (μg/mL) Fold Reduction of |